Quantitative Phase Microscopy is so-called holography microscope which can measure quantitative information based on thickness of the sample and index of refraction using optical interference technology. The optical interference technology that we are dealing with is called Quantitative Phase Imaging (QPI). Introducing this technology to the optical microscope is called Quantitative Phase Microscopy. Using QPM, quantitative information based on the thickness of transparent specimen, such as glass and cells, and index of refraction can be measured fast and accurately with the non-invasive and non-contact manner. For further technical information regarding QPM, please visit Hamamatsu Photonics K.K. website.

Comparison with the QPM and other microscope
  • EM : Electron microscope
    The electron microscope is high-resolution device but it is not suitable for the dynamic observation for biological cells.
  • BFM : Bright field microscope
    It is necessary to dye non-invasively for observing the transparent cells.
  • PCM : Phase-contrast microscope
    It can visualize two-dimensional cells but not quantitative.
  • QPM : Quantitative phase microscope
    QPM can measure three-dimensional quantitative information ( = the product of thickness and index of refraction margin) for biological cells.

Followings are the measurement service and equipment we deal in.

  • The contract measurement service of the transparent specimen, such as optical device, glass, biological cells etc…, for using QPM.
  • QPI unit which can be expandable to QPM.
  • QPM system consists of light source, inverted microscope, QPI unit, camera and QPI software.